I thought the following snippet from a somewhat edited email I recently wrote in reply to a question about random slopes and what it means that an effect becomes insignificant might be helpful to some. I also took it as an opportunity to updated the procedure I described at http://hlplab.wordpress.com/2009/05/14/random-effect-structure/. As always, comments are welcome. What I am writing below are just suggestions.
[...] an insignificant effect in an (1 + factor|subj) model means that, after controlling for random by-subject variation in the slope/effect of factor, you find no (by-convention-significant) evidence for the effect. Like you suggest, this is due to the fact that there is between-subject variability in the slope that is sufficiently large to let us call into question the hypothesis that the ‘overall’ slope is significantly different from zero.
[...] So, what’s the rule of thumb here? If you run any of the standard simple designs (2×2, 2×3, 2x2x2,etc.) and you have the psychologist’s luxury of plenty of data (24+item, 24+ subject [...]), the full random effect structure is something you should entertain as your starting point. That’s in Clark’s spirit. That’s what F1 and F2 were meant for. [...] All of these approaches do not just capture random intercept differences by subject and item. They also aim to capture random slope differences.
[...] here’s what I’d recommend during tutorials now because it often saves time for psycholinguistic data. I am only writing down the random effects but, of course, I am assuming there are fixed effects, too, and that your design factors will remain in the model. Let’s look at a 2×2 design: Continue reading ‘More on random slopes and what it means if your effect is not longer significant after the inclusion of random slopes’